mouse VASH1 shRNA silencing AAV

Name
AAV-m-VASH1-shRNA

Cat No
shAAV-275966

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Vash1.

shAAV-275966

AAV-m-VASH1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Vash1 (vasohibin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI834978; D930046M13Rik; G630009D10Rik

Description (Vector)

Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.

Gene ID

238328

Gene Name (Vector)

vasohibin 1

Gene Symbol

Vash1

ORF Size (aa)

870

ORF Size (bp)

870 bp

RefSeq ID

NM_177354

RefSeq Synonyms

NM_177354, BC086688,

Species

mouse

UniGene ID

Mm.216101

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.