mouse USP16 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Usp16.
shAAV-275716
AAV-m-USP16-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Usp16 (ubiquitin specific peptidase 16). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200004E02Rik; 2810483I07Rik; 6330514E22Rik; UBPM
Description (Vector)
Specifically deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-10' of histone H3, and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
Gene ID
74112
Gene Name (Vector)
ubiquitin specific peptidase 16
Gene Symbol
Usp16
ORF Size (aa)
2478
ORF Size (bp)
2478 bp
RefSeq ID
NM_024258
RefSeq Synonyms
NM_024258, BC003278,
Species
mouse
UniGene ID
Mm.152941
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.