mouse UNC13B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Unc13b.
shAAV-275630
AAV-m-UNC13B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Unc13b (unc-13 homolog B (C. elegans)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Munc13-1; Munc13-2; Unc13a; Unc13h1; Unc13h2
Description (Vector)
Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Gene ID
22249
Gene Name (Vector)
unc-13 homolog B (C. elegans)
Gene Symbol
Unc13b
ORF Size (aa)
4806
ORF Size (bp)
4806 bp
RefSeq ID
NM_001081413
RefSeq Synonyms
NM_021468, NM_001310758, NM_001081413, BC166023, BC158025, BC157967,
Species
mouse
UniGene ID
Mm.128892
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.