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mouse TRPM2 shRNA silencing AAV

Name 
AAV-m-TRPM2-shRNA
Cat No 
shAAV-275095
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Trpm2.

shAAV-275095
AAV-m-TRPM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Trpm2 (transient receptor potential cation channel, subfamily M, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9830168K16Rik; C79133; LTRPC2; Trp7; TRPC7; Trrp7
Description (Vector)
Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Gene ID
28240
Gene Name (Vector)
transient receptor potential cation channel, subfamily M, member 2
Gene Symbol
Trpm2
ORF Size (aa)
4521
ORF Size (bp)
4521 bp
RefSeq ID
NM_138301
RefSeq Synonyms
NM_138301, BC141391,
Species
mouse
UniGene ID
Mm.276762

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.