mouse TPM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tpm2.
shAAV-274854
AAV-m-TPM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tpm2 (tropomyosin 2, beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Tpm-2; Trop-2
Description (Vector)
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization (By similarity).
Gene ID
22004
Gene Name (Vector)
tropomyosin 2, beta
Gene Symbol
Tpm2
ORF Size (aa)
927
ORF Size (bp)
927 bp
RefSeq ID
NM_009416
RefSeq Synonyms
NM_009416, NM_001277876, NM_001277875, BC024358, BC014809,
Species
mouse
UniGene ID
Mm.646
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.