mouse TNFRSF1A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tnfrsf1a.
shAAV-274706
AAV-m-TNFRSF1A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD120a; FPF; p55; p55-R; TNF-alphaR1; TNF-R; TNF-R-I; TNF-R1; TNF-R55; TNFalpha-R1; TNFAR; Tnfr-2; Tnfr1; TNFR60; TNFRI; TNFRp55
Description (Vector)
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Gene ID
21937
Gene Name (Vector)
tumor necrosis factor receptor superfamily, member 1a
Gene Symbol
Tnfrsf1a
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_011609
RefSeq Synonyms
NM_011609, BC052675, BC004599,
Species
mouse
UniGene ID
Mm.474976
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.