mouse TLR2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tlr2.
shAAV-274278
AAV-m-TLR2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tlr2 (toll-like receptor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Ly105
Description (Vector)
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.
Gene ID
24088
Gene Name (Vector)
toll-like receptor 2
Gene Symbol
Tlr2
ORF Size (aa)
2355
ORF Size (bp)
2355 bp
RefSeq ID
NM_011905
RefSeq Synonyms
NM_011905, BC014693,
Species
mouse
UniGene ID
Mm.87596
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.