mouse TLK2 shRNA silencing AAV

Name 
AAV-m-TLK2-shRNA
Cat No 
shAAV-274266
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse TLK2.

shAAV-274266
AAV-m-TLK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse TLK2 (tousled-like kinase 2 (Arabidopsis)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4933403M19Rik; PKU-alpha; PKUalpha; Tlk
Description (Vector)
Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy.
Gene ID
24086
Gene Name (Vector)
tousled-like kinase 2 (Arabidopsis)
Gene Symbol
TLK2
ORF Size (aa)
2151
ORF Size (bp)
2151 bp
RefSeq ID
NM_011903
RefSeq Synonyms
NM_011903, NM_001294334, NM_001294331, NM_001294330, NM_001294329, NM_001112705, BC140390,
Species
mouse
UniGene ID
Mm.126976

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.