mouse TCFAP2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tfap2a.
shAAV-273925
AAV-m-TCFAP2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tfap2a (transcription factor AP-2, alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AP-2; Ap-2 (a); Ap2; AP2alpha; Ap2tf; Tcfap2a
Description (Vector)
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
Gene ID
21418
Gene Name (Vector)
transcription factor AP-2, alpha
Gene Symbol
Tfap2a
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
RefSeq ID
NM_011547
RefSeq Synonyms
NM_011547, NM_001301674, NM_001122948, BC018226, BC007471,
Species
mouse
UniGene ID
Mm.85544
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.