mouse STRA13 shRNA silencing AAV

Name
AAV-m-STRA13-shRNA

Cat No
shAAV-273379

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Cenpx.

shAAV-273379

AAV-m-STRA13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cenpx (centromere protein X). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Stra13

Description (Vector)

DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation.

Gene ID

20892

Gene Name (Vector)

centromere protein X

Gene Symbol

Cenpx

ORF Size (aa)

237

RefSeq ID

NM_016665

RefSeq Synonyms

NM_016665, NM_001347612, NM_001347611, BC156610,

Species

mouse

UniGene ID

Mm.259716

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.