mouse SREBF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Srebf2.
shAAV-273128
AAV-m-SREBF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Srebf2 (sterol regulatory element binding factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI608257; bHLHd2; lop13; nuc; SREBP-2; SREBP2; SREBP2gc
Description (Vector)
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Gene ID
20788
Gene Name (Vector)
sterol regulatory element binding factor 2
Gene Symbol
Srebf2
ORF Size (aa)
3393
ORF Size (bp)
3393 bp
RefSeq ID
NM_033218
RefSeq Synonyms
NM_033218, BC167259,
Species
mouse
UniGene ID
Mm.38016
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.