mouse SQSTM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sqstm1.
shAAV-273112
AAV-m-SQSTM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sqstm1 (sequestosome 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A170; OSF-6; Osi; p62; STAP; STONE14
Description (Vector)
Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
Gene ID
18412
Gene Name (Vector)
sequestosome 1
Gene Symbol
Sqstm1
ORF Size (aa)
1215
ORF Size (bp)
1215 bp
RefSeq ID
NM_011018
RefSeq Synonyms
NM_011018, NM_001290769, BC006019,
Species
mouse
UniGene ID
Mm.40828
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.