mouse SPOP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Spop.
shAAV-273054
AAV-m-SPOP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Spop (speckle-type POZ protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI315626; Pcif1; TEF2
Description (Vector)
Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.
Gene ID
20747
Gene Name (Vector)
speckle-type POZ protein
Gene Symbol
Spop
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
RefSeq ID
NM_025287
RefSeq Synonyms
NM_025287, BC045205, BC043131,
Species
mouse
UniGene ID
Mm.395285
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.