mouse SNRPC shRNA silencing AAV

Name
AAV-m-SNRPC-shRNA

Cat No
shAAV-272760

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Snrpc.

shAAV-272760

AAV-m-SNRPC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Snrpc (U1 small nuclear ribonucleoprotein C). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Snrp1c; U1-C; U1C

Description (Vector)

Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.

Gene ID

20630

Gene Name (Vector)

U1 small nuclear ribonucleoprotein C

Gene Symbol

Snrpc

ORF Size (aa)

480

ORF Size (bp)

480 bp

RefSeq ID

NM_011432

RefSeq Synonyms

NM_011432, BC092266, BC008243,

Species

mouse

UniGene ID

Mm.308514

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.