mouse SNCA shRNA silencing AAV

Name 
AAV-m-SNCA-shRNA
Cat No 
shAAV-272717
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Snca.

shAAV-272717
AAV-m-SNCA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Snca (synuclein, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alphaSYN; NACP
Description (Vector)
SNCA may be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Gene ID
20617
Gene Name (Vector)
synuclein, alpha
Gene Symbol
Snca
ORF Size (aa)
423
RefSeq ID
NM_009221
RefSeq Synonyms
NM_009221, NM_001042451, BC046764,
Species
mouse
UniGene ID
Mm.17484

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.