mouse SMAD6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Smad6.
shAAV-272604
AAV-m-SMAD6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Smad6 (SMAD family member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
b2b390Clo; Madh6
Description (Vector)
Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.
Gene ID
17130
Gene Name (Vector)
SMAD family member 6
Gene Symbol
Smad6
ORF Size (aa)
1488
ORF Size (bp)
1488 bp
RefSeq ID
NM_008542
RefSeq Synonyms
NM_008542, BC047280,
Species
mouse
UniGene ID
Mm.325757
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.