human SMAD6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SMAD6.
shAAV-223694
AAV-h-SMAD6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SMAD6 (SMAD family member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HsT17432; MADH6; MADH7;
Description (Vector)
SMAD6 belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4091
Gene Name (Vector)
SMAD family member 6
Gene Symbol
SMAD6
HGNC ID
HGNC:6772
ORF Size (aa)
1491
ORF Size (bp)
1491 bp
RefSeq ID
NM_005585
RefSeq Synonyms
NM_005585, NM_001142861, BC012986,
Species
human
UniGene ID
Hs.153863
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.