mouse SLC4A8 shRNA silencing AAV

Name 
AAV-m-SLC4A8-shRNA
Cat No 
shAAV-272452
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Slc4a8.

shAAV-272452
AAV-m-SLC4A8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Slc4a8 (solute carrier family 4 (anion exchanger), member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW493845; C230026C11; kNBC-3; NDCBE
Description (Vector)
Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Gene ID
59033
Gene Name (Vector)
solute carrier family 4 (anion exchanger), member 8
Gene Symbol
Slc4a8
ORF Size (aa)
3270
ORF Size (bp)
3270 bp
RefSeq ID
NM_021530
RefSeq Synonyms
NM_021530, NM_001347102, BC030388,
Species
mouse
UniGene ID
Mm.209856

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.