human SLC4A8 shRNA silencing AAV

Name 
AAV-h-SLC4A8-shRNA
Cat No 
shAAV-223528
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC4A8.

shAAV-223528
AAV-h-SLC4A8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC4A8 (solute carrier family 4 member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NBC3; NDCBE
Description (Vector)
SLC4A8 is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
9498
Gene Name (Vector)
solute carrier family 4 member 8
Gene Symbol
SLC4A8
HGNC ID
HGNC:11034
ORF Size (aa)
2076
ORF Size (bp)
2076 bp
RefSeq ID
NM_004858
RefSeq Synonyms
NM_004858, NM_001267615, NM_001258403, NM_001258402, NM_001258401, NM_001039960, BC025994,
Species
human
UniGene ID
Hs.370636

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.