mouse SCN9A shRNA silencing AAV

Name 
AAV-m-SCN9A-shRNA
Cat No 
shAAV-271454
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse SCN9A.

shAAV-271454
AAV-m-SCN9A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse SCN9A (sodium channel, voltage-gated, type IX, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KIAA4197; mKIAA4197; Nav1.7; PN1; Scn1a;
Description (Vector)
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (By similarity).
Gene ID
20274
Gene Name (Vector)
sodium channel, voltage-gated, type IX, alpha
Gene Symbol
SCN9A
ORF Size (aa)
5955
ORF Size (bp)
5955 bp
RefSeq ID
NM_018852
RefSeq Synonyms
NM_018852, NM_001290675, NM_001290674, BC172761, BC172147, BC158048,
Species
mouse
UniGene ID
Mm.440889

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.