mouse RYBP shRNA silencing AAV

Name
AAV-m-RYBP-shRNA

Cat No
shAAV-271277

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Rybp.

shAAV-271277

AAV-m-RYBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rybp (RING1 and YY1 binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2410018J24Rik; DEDAF; YEAF1

Description (Vector)

Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.

Gene ID

56353

Gene Name (Vector)

RING1 and YY1 binding protein

Gene Symbol

Rybp

ORF Size (aa)

687

RefSeq ID

NM_019743

RefSeq Synonyms

NM_019743, BC138325, BC138324, BC080287, BC053016,

Species

mouse

UniGene ID

Mm.321633

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.