mouse SRCIN1 shRNA silencing AAV

Name 
AAV-m-SRCIN1-shRNA
Cat No 
shAAV-270800
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Srcin1.

shAAV-270800
AAV-m-SRCIN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Srcin1 (SRC kinase signaling inhibitor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mKIAA1684; P140; p140Cap; SNIP
Description (Vector)
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
Gene ID
56013
Gene Name (Vector)
SRC kinase signaling inhibitor 1
Gene Symbol
Srcin1
ORF Size (aa)
3651
ORF Size (bp)
3651 bp
RefSeq ID
NM_018873
RefSeq Synonyms
NM_018873, BC156441,
Species
mouse
UniGene ID
Mm.342665

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.