mouse RGS19 shRNA silencing AAV

Name 
AAV-m-RGS19-shRNA
Cat No 
shAAV-270487
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Rgs19.

shAAV-270487
AAV-m-RGS19-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Rgs19 (regulator of G-protein signaling 19). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610042F04Rik; AI324841; AW547781; GAIP
Description (Vector)
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Gene ID
56470
Gene Name (Vector)
regulator of G-protein signaling 19
Gene Symbol
Rgs19
ORF Size (aa)
651
RefSeq ID
NM_026446
RefSeq Synonyms
NM_026446, NM_001291210, NM_001291209, NM_001291208, NM_001291207, NM_001291206, NM_001291205, BC003838,
Species
mouse
UniGene ID
Mm.274366

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.