mouse PTPRC shRNA silencing AAV

Name 
AAV-m-PTPRC-shRNA
Cat No 
shAAV-269814
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ptprc.

shAAV-269814
AAV-m-PTPRC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ptprc (protein tyrosine phosphatase, receptor type, C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B220; Cd45; CD45R; L-CA; loc; Ly-5; Lyt-4; T200
Description (Vector)
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Gene ID
19264
Gene Name (Vector)
protein tyrosine phosphatase, receptor type, C
Gene Symbol
Ptprc
ORF Size (aa)
3459
ORF Size (bp)
3459 bp
RefSeq ID
NM_011210
RefSeq Synonyms
NM_011210, NM_001268286, NM_001111316, BC167212,
Species
mouse
UniGene ID
Mm.391573

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.