mouse PTGER3 shRNA silencing AAV

Name
AAV-m-PTGER3-shRNA

Cat No
shAAV-269740

Availability
Immediate

This is an AAV expressing shRNA for silencing of Mouse Ptger3.

shAAV-269740

AAV-m-PTGER3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ptger3 (prostaglandin E receptor 3 (subtype EP3)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EP3; Pgerep3; Ptgerep3

Description (Vector)

Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).

Gene ID

19218

Gene Name (Vector)

prostaglandin E receptor 3 (subtype EP3)

Gene Symbol

Ptger3

ORF Size (aa)

1089

ORF Size (bp)

1089 bp

RefSeq ID

NM_011196

RefSeq Synonyms

NM_011196, BC058742,

Species

mouse

UniGene ID

Mm.30424

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.