mouse PTCH1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ptch1.
shAAV-269719
AAV-m-PTCH1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ptch1 (patched 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A230106A15Rik; mes; Ptc; Ptc1; Ptch
Description (Vector)
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Gene ID
19206
Gene Name (Vector)
patched 1
Gene Symbol
Ptch1
ORF Size (aa)
4302
ORF Size (bp)
4302 bp
RefSeq ID
NM_008957
RefSeq Synonyms
NM_008957, NM_001328514, BC157045, BC156082,
Species
mouse
UniGene ID
Mm.228798
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.