mouse PSMB4 shRNA silencing AAV

Cat. No: shAAV-269637

Availability: 4-5 weeks

Name: AAV-m-PSMB4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Psmb4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Psmb4
Gene Name: proteasome (prosome, macropain) subunit, beta type 4
Gene ID: 19172
Gene Synonyms: Pros-27
ORF Size: 795 bp
RefSeq#: NM_008945
Gene Description: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome (By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
UniGene ID: Mm.368