mouse PPM1A shRNA silencing AAV

Name 
AAV-m-PPM1A-shRNA
Cat No 
shAAV-269161
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppm1a.

shAAV-269161
AAV-m-PPM1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppm1a (protein phosphatase 1A, magnesium dependent, alpha isoform). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310003C21Rik; 2900017D14Rik; AI427932; AU017636; MMPa-2; MPPa-1
Description (Vector)
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.
Gene ID
19042
Gene Name (Vector)
protein phosphatase 1A, magnesium dependent, alpha isoform
Gene Symbol
Ppm1a
ORF Size (aa)
1149
ORF Size (bp)
1149 bp
RefSeq ID
NM_008910
RefSeq Synonyms
NM_008910, BC008595,
Species
mouse
UniGene ID
Mm.261045

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.