mouse PNKP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pnkp.
shAAV-268948
AAV-m-PNKP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pnkp (polynucleotide kinase 3′- phosphatase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1810009G08Rik; PNK
Description (Vector)
Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
Gene ID
59047
Gene Name (Vector)
polynucleotide kinase 3'- phosphatase
Gene Symbol
Pnkp
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_021549
RefSeq Synonyms
NM_021549, NM_001290767, NM_001290766, NM_001290764, BC057659,
Species
mouse
UniGene ID
Mm.238254
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.