mouse PDX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pdx1.
shAAV-268353
AAV-m-PDX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pdx1 (pancreatic and duodenal homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IDX-1; IPF-1; Ipf1; Mody4; pdx-1; STF-1
Description (Vector)
Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.
Gene ID
18609
Gene Name (Vector)
pancreatic and duodenal homeobox 1
Gene Symbol
Pdx1
ORF Size (aa)
855
ORF Size (bp)
855 bp
RefSeq ID
NM_008814
RefSeq Synonyms
NM_008814, BC105642, BC103582, BC103581, BC103572,
Species
mouse
UniGene ID
Mm.389714
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.