mouse PCGF6 shRNA silencing AAV

Name
AAV-m-PCGF6-shRNA

Cat No
shAAV-268216

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Pcgf6.

shAAV-268216

AAV-m-PCGF6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pcgf6 (polycomb group ring finger 6). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4933407A11Rik; AI604840; MBLR; Rnf134

Description (Vector)

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene ID

71041

Gene Name (Vector)

polycomb group ring finger 6

Gene Symbol

Pcgf6

ORF Size (aa)

1062

RefSeq ID

NM_027654

RefSeq Synonyms

NM_027654, BC089460, BC016195,

Species

mouse

UniGene ID

Mm.35413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.