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mouse PARD6B shRNA silencing AAV

Name 
AAV-m-PARD6B-shRNA
Cat No 
shAAV-268066
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pard6b.

shAAV-268066
AAV-m-PARD6B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pard6b (par-6 family cell polarity regulator beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AV025615; Par6b
Description (Vector)
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Gene ID
58220
Gene Name (Vector)
par-6 family cell polarity regulator beta
Gene Symbol
Pard6b
ORF Size (aa)
897
ORF Size (bp)
897 bp
RefSeq ID
NM_021409
RefSeq Synonyms
NM_021409, BC025147,
Species
mouse
UniGene ID
Mm.292834

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.