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human CD1C shRNA silencing Adenovirus

Name 
Ad-h-CD1C-shRNA
Cat No 
shADV-204594
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CD1C.

shADV-204594
Ad-h-CD1C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CD1C (CD1c molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BDCA1; CD1; CD1A; R7
Description (Vector)
CD1C encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Gene ID
911
Gene Name (Vector)
CD1c molecule
Gene Symbol
CD1C
HGNC ID
HGNC:1636
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_001765
RefSeq Synonyms
NM_001765, BC126467, BC126465,
Species
human
UniGene ID
Hs.132448

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.