mouse PAPPA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pappa.
shAAV-268049
AAV-m-PAPPA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pappa (pregnancy-associated plasma protein A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
8430414N03Rik; IGFBP-4ase; PAG1; PAPP-A
Description (Vector)
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
Gene ID
18491
Gene Name (Vector)
pregnancy-associated plasma protein A
Gene Symbol
Pappa
ORF Size (aa)
4872
ORF Size (bp)
4872 bp
RefSeq ID
NM_021362
RefSeq Synonyms
NM_021362, BC156243,
Species
mouse
UniGene ID
Mm.317854
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.