human PAPPA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PAPPA.
shAAV-218197
AAV-h-PAPPA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PAPPA (pappalysin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASBABP2; DIPLA1; IGFBP-4ase; PAPA; PAPP-A; PAPPA1
Description (Vector)
PAPPA encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
Gene ID
5069
Gene Name (Vector)
pappalysin 1
Gene Symbol
PAPPA
HGNC ID
HGNC:8602
ORF Size (aa)
4884
ORF Size (bp)
4884 bp
RefSeq ID
NM_002581
RefSeq Synonyms
NM_002581, BC078657,
Species
human
UniGene ID
Hs.643599
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.