mouse PAG1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pag1.
shAAV-268004
AAV-m-PAG1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pag1 (phosphoprotein associated with glycosphingolipid microdomains 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cbp; F730007C19Rik; Pag
Description (Vector)
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Gene ID
94212
Gene Name (Vector)
phosphoprotein associated with glycosphingolipid microdomains 1
Gene Symbol
Pag1
ORF Size (aa)
1290
ORF Size (bp)
1290 bp
RefSeq ID
NM_053182
RefSeq Synonyms
NM_053182, NM_001195031, BC145763, BC145761, BC145328,
Species
mouse
UniGene ID
Mm.214484
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.