mouse P2RX7 shRNA silencing AAV

Name 
AAV-m-P2RX7-shRNA
Cat No 
shAAV-267945
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse P2rx7.

shAAV-267945
AAV-m-P2RX7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse P2rx7 (purinergic receptor P2X, ligand-gated ion channel, 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI467586; P2X(7); P2X7R
Description (Vector)
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Gene ID
18439
Gene Name (Vector)
purinergic receptor P2X, ligand-gated ion channel, 7
Gene Symbol
P2rx7
ORF Size (aa)
1788
ORF Size (bp)
1788 bp
RefSeq ID
NM_011027
RefSeq Synonyms
NM_011027, NM_001284402, NM_001038887, NM_001038845, NM_001038839, BC141120,
Species
mouse
UniGene ID
Mm.42026

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.