mouse OCA2 shRNA silencing AAV

Name 
AAV-m-OCA2-shRNA
Cat No 
shAAV-266309
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Oca2.

shAAV-266309
AAV-m-OCA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Oca2 (oculocutaneous albinism II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D7H15S12; D7Icr28RN; D7Nic1; p; p<cas>
Description (Vector)
Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color.
Gene ID
18431
Gene Name (Vector)
oculocutaneous albinism II
Gene Symbol
Oca2
ORF Size (aa)
2502
ORF Size (bp)
2502 bp
RefSeq ID
NM_021879
RefSeq Synonyms
NM_021879, BC120549, BC119220,
Species
mouse
UniGene ID
Mm.137052

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.