mouse NKX2-2 shRNA silencing AAV

Name 
AAV-m-NKX2-2-shRNA
Cat No 
shAAV-265814
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nkx2-2.

shAAV-265814
AAV-m-NKX2-2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nkx2-2 (NK2 homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Nkx-2.2; Nkx2.2; tinman
Description (Vector)
Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity).
Gene ID
18088
Gene Name (Vector)
NK2 homeobox 2
Gene Symbol
Nkx2-2
ORF Size (aa)
822
ORF Size (bp)
822 bp
RefSeq ID
NM_010919
RefSeq Synonyms
NM_010919, NM_001077632, BC138160, BC138159,
Species
mouse
UniGene ID
Mm.330639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.