mouse NFAM1 shRNA silencing AAV

Name
AAV-m-NFAM1-shRNA

Cat No
shAAV-265701

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Nfam1.

shAAV-265701

AAV-m-NFAM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nfam1 (Nfat activating molecule with ITAM motif 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4921501M20Rik; Cnaip

Description (Vector)

NFAM1 may function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

Gene ID

74039

Gene Name (Vector)

Nfat activating molecule with ITAM motif 1

Gene Symbol

Nfam1

ORF Size (aa)

642

RefSeq ID

NM_028728

RefSeq Synonyms

NM_028728, NM_001271414, NM_001271413, NM_001271412, NM_001271411, BC150488,

Species

mouse

UniGene ID

Mm.32584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.