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mouse MTAP1B shRNA silencing AAV

Name 
AAV-m-MTAP1B-shRNA
Cat No 
shAAV-265092
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Map1b.

shAAV-265092
AAV-m-MTAP1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Map1b (microtubule-associated protein 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A230055D22; AI843217; LC1; MAP5; Mtap-5; Mtap1b; Mtap5
Description (Vector)
Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
Gene ID
17755
Gene Name (Vector)
microtubule-associated protein 1B
Gene Symbol
Map1b
ORF Size (aa)
7395
ORF Size (bp)
7395 bp
RefSeq ID
NM_008634
RefSeq Synonyms
NM_008634, BC138034, BC138033,
Species
mouse
UniGene ID
Mm.474896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.