mouse MPZL1 shRNA silencing AAV

Name
AAV-m-MPZL1-shRNA

Cat No
shAAV-264860

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Mpzl1.

shAAV-264860

AAV-m-MPZL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mpzl1 (myelin protein zero-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1110007A10Rik; PZR

Description (Vector)

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Gene ID

68481

Gene Name (Vector)

myelin protein zero-like 1

Gene Symbol

Mpzl1

ORF Size (aa)

630

ORF Size (bp)

630 bp

RefSeq ID

NM_001001880

RefSeq Synonyms

NM_001347128, NM_001083897, NM_001001880, BC072563,

Species

mouse

UniGene ID

Mm.46438

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.