mouse MKL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mkl1.
shAAV-264671
AAV-m-MKL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mkl1 (MKL (megakaryoblastic leukemia)/myocardin-like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AMKL; Bsac; Mal; Mrtf-A
Description (Vector)
Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation (By similarity).
Gene ID
223701
Gene Name (Vector)
MKL (megakaryoblastic leukemia)/myocardin-like 1
Gene Symbol
Mkl1
ORF Size (aa)
2790
ORF Size (bp)
2790 bp
RefSeq ID
NM_153049
RefSeq Synonyms
NM_153049, NM_001082536, BC050941,
Species
mouse
UniGene ID
Mm.439814
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.