mouse MICAL3 shRNA silencing AAV

Cat. No: shAAV-264627

Availability: 4-5 weeks

Name: AAV-m-MICAL3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mical3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mical3
Gene Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Gene ID: 194401
Gene Synonyms: C130040D16Rik; Mical-3; mKIAA1364
ORF Size: 2595 bp
RefSeq#: NM_153396
Gene Description: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (By similarity). Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this process.
UniGene ID: Mm.122399