mouse MCL1 shRNA silencing AAV

Name
AAV-m-MCL1-shRNA

Cat No
shAAV-264366

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Mcl1.

shAAV-264366

AAV-m-MCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mcl1 (myeloid cell leukemia sequence 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AW556805; Mcl-1

Description (Vector)

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Gene ID

17210

Gene Name (Vector)

myeloid cell leukemia sequence 1

Gene Symbol

Mcl1

ORF Size (aa)

996

ORF Size (bp)

996 bp

RefSeq ID

NM_008562

RefSeq Synonyms

NM_008562, BC021638, BC005427, BC003839,

Species

mouse

UniGene ID

Mm.1639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.