mouse MCF2L shRNA silencing AAV

Name 
AAV-m-MCF2L-shRNA
Cat No 
shAAV-264362
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mcf2l.

shAAV-264362
AAV-m-MCF2L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mcf2l (mcf.2 transforming sequence-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C130040G20Rik; Dbs; mKIAA0362; Ost
Description (Vector)
Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Gene ID
17207
Gene Name (Vector)
mcf.2 transforming sequence-like
Gene Symbol
Mcf2l
ORF Size (aa)
3501
ORF Size (bp)
3501 bp
RefSeq ID
NM_178076
RefSeq Synonyms
NM_178076, NM_001159486, NM_001159485, BC058622,
Species
mouse
UniGene ID
Mm.334413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.