mouse MAP2K5 shRNA silencing AAV

Name 
AAV-m-MAP2K5-shRNA
Cat No 
shAAV-264174
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Map2k5.

shAAV-264174
AAV-m-MAP2K5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Map2k5 (mitogen-activated protein kinase kinase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI324775; AI428457; Mapkk5; MEK5; Prkmk5
Description (Vector)
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
Gene ID
23938
Gene Name (Vector)
mitogen-activated protein kinase kinase 5
Gene Symbol
Map2k5
ORF Size (aa)
1320
ORF Size (bp)
1320 bp
RefSeq ID
NM_011840
RefSeq Synonyms
NM_011840, BC028260,
Species
mouse
UniGene ID
Mm.325746

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.