mouse LPXN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Lpxn.
shAAV-263789
AAV-m-LPXN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Lpxn (leupaxin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4933402K05Rik; A530083L21Rik; AV278559; LDPL
Description (Vector)
Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.
Gene ID
107321
Gene Name (Vector)
leupaxin
Gene Symbol
Lpxn
ORF Size (aa)
1161
RefSeq ID
NM_134152
RefSeq Synonyms
NM_134152, BC026563,
Species
mouse
UniGene ID
Mm.313136
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.