mouse LPCAT2 shRNA silencing AAV

Name
AAV-m-LPCAT2-shRNA

Cat No
shAAV-263773

Availability
Immediate

This is an AAV expressing shRNA for silencing of Mouse Lpcat2.

shAAV-263773

AAV-m-LPCAT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lpcat2 (lysophosphatidylcholine acyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A330042H22; Aytl1; Aytl1a; lpafat1

Description (Vector)

Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases (By similarity).

Gene ID

270084

Gene Name (Vector)

lysophosphatidylcholine acyltransferase 2

Gene Symbol

Lpcat2

ORF Size (aa)

1635

ORF Size (bp)

1635 bp

RefSeq ID

NM_173014

RefSeq Synonyms

NM_173014, BC160287, BC150666, BC144806,

Species

mouse

UniGene ID

Mm.21463

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.