mouse LEP shRNA silencing AAV

Name
AAV-m-LEP-shRNA

Cat No
shAAV-263379

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Lep.

shAAV-263379

AAV-m-LEP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lep (leptin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ob; obese

Description (Vector)

LEP may function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.

Gene ID

16846

Gene Name (Vector)

leptin

Gene Symbol

Lep

ORF Size (aa)

504

RefSeq ID

NM_008493

RefSeq Synonyms

NM_008493, BC125245,

Species

mouse

UniGene ID

Mm.277072

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.